Premier Research Labs B12-ND Liquid 54ml

Premier Research Labs B-12ND Liquid is a revolutionary, highly absorbable delivery system made with signature fermented probiotic-cultured technology. Through a micro-cultured delivery system, it is the first B12 nutraceutical preparation designed to assure rapid absorption of these blood circulating forms of B-2. Even those with poor digestion can enjoy the full benefits of B12’s highly bio-available co-enzyme B12 liquid nutrients. No other form of B-12 can offer this type of bio-availability and quality.

There are four types of supplemental B12 available: methylcobalamin, hydroxocobalamin, adenosylcobalamin, and cyanocobalamin. The first three are naturally present in foods. Cyanocobalamin is a synthetic form that can be converted into adenosylcobalamin and methylcobalamin, but its bioavailability is poor compared to the other forms. Cyanocobalamin also introduces cyanide into the body as a result of its metabolism which is not something we desire.

For many vegan and vegetarian individuals, it may be difficult to get a sufficient amount of vitamin B12 from their diet because the sources of vitamin B12 are of animal origin. B12 is the only vitamin that contains a trace element (cobalt), which is why it’s called cobalamin. Cobalamin is produced in the gut of animals. It’s the only vitamin we can’t obtain from plants or sunlight. Plants don’t need B12, so they don’t store it. Plant foods said to contain B12 actually contain B12 analogs called cobamides that block the intake of and increase the need for true B12.

If an individual is vegetarian or vegan supplementing with B12 indefinitely is a wise move as the risk of B12 deficiency is high and the effects of B12 deficiency are potentially irreversible. As B12 supplements are water soluble they are considered nontoxic even at high daily amounts.

In general, the following groups are at greatest risk for a deficiency:

• Vegetarians and vegans
• People aged 60 or over
• People who regularly use PPIs or acid-suppressing drugs
• People on diabetes drugs like metformin
• People with Crohn’s disease, ulcerative colitis, celiac, or IBS
• Women with a history of infertility and miscarriage

Vitamin B12 works together with folate in the synthesis of DNA and red blood cells. It’s also involved in the production of the myelin sheath around the nerves and the conduction of nerve impulses. B12 deficiency can mimic the signs of Alzheimer’s, dementia, multiple sclerosis, and several mental illnesses.

Here are some of the most common vitamin B12 deficiency symptoms:

• Tingling or numbness in the hands and feet
• Brain fog, confusion, and memory problems
• Depression
• Premature aging
• Cognitive decline
• Anemia
• Weakness
• Fatigue
• Reduced appetite and weight loss
• Constipation
• Trouble balancing

Children can also show symptoms including developmental issues and learning disabilities if their B12 levels are too low. Spatial ability, fluid intelligence and short term memory are all impacted.